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Super User

Alicia Henn has been the Chief Scientific Officer of BioSpherix, Ltd since 2013. Previously, she was a researcher at the Center for Biodefense Immune Modeling in Rochester, NY. Alicia obtained her PhD in molecular pharmacology and cancer therapeutics from Roswell Park Cancer Institute in Buffalo, NY and her MBA from the Simon School at University of Rochester in Rochester, NY.

Circadian Rhythm

Circadian Rhythm reproducibly model hypoxia-circadian patterns Cell Equipment ProOx C21 & C-Chamber Cell Research - hypoxia chamber with static control of O2 and CO2 - C21 & C-Chamber OxyCycler C42 & C-Chamber Cell Research -...

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Cell Imaging

Cell Imaging Cellular imaging with a BioSpherix oxygen chamber can help you achieve the following: image cells within non-interrupted, physiologically relevant conditions Cell Equipment ProOx C21 & C-Chamber Cell Research - physiologic...

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Cell Cycle

Cell Cycle / Cell Death Using BioSpherix's oxygen incubators and chambers are effective for monitoring the following aspects of cell cycle and death: simulate cellular physiological O2 levels reduce DNA damage remove ROS/oxidative stress artifact induce...

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Cell Analysis

Cell Analysis Controlled conditions are important for cell analysis. Today, most cell-based assays are performed in standard CO2 incubators, open BSCs, and room-air cell analyzers. Assay conditions in CO2 incubators vary greatly and never resemble the...

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Cardiovascular

Cardiovascular simulate cardiac tissue O2 levels promote cardiac lineage differentiation induce VEGF expression and angiogenesis reproducibly model myocardial ischemia reperfusion injury Cell Equipment ProOx C21 & C-Chamber Cell Research -...

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Metabolism

Metabolism / Mitochondria Aerobic metabolism is an efficient pathway for ATP production in mammalian cells. However, ‘standard’ cell culture methods include non-physiological exposures to both antibiotics and also room-air levels of oxygen. While...

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Intermittent Hypoxia

Intermittent Hypoxia Programmed control of dynamic oxygen conditions permit a range of biological modeling possibilities. Chambers for in vitro and in vivo exposures permit highly reproducible experiments using intermittent hypoxia (IH), acute intermittent...

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Carbon Monoxide

Carbon Monoxide Learn about carbon monoxide applications for therapy below. Carbon monoxide is an endogenously produced signaling gas that is produced in the human body. An important biological regulator, CO has been established as a modulator of vascular...

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Toxicology

Toxicology - In Vitro Oxygen is an important regulator of cell function. Physiologic O2 (or physioxia) is much lower than oxygen levels provided in most cell-based toxicology assays (room air - 21% oxygen). In the body, cells experience a range of tissue...

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Neuroscience

Neuroscience Oxygen is an important physiological parameter in healthy neural tissues. Levels range 1-6% O2 for neurons and glial cells. They never experience the 21% O2 (room air oxygen) used in most cell-based neuroscience studies. Since oxygen modulates...

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